Tear proteins implicated in defence and their corresponding genes: tear lipocalin has recently been demonstrated to be expressed4 in the secretory cells of the tracheal epithelium. However, no data are at present available on its presence in the bronchial mucus
Protein | Protein distribution | Corresponding gene | Chromosomal localisation | ||||
---|---|---|---|---|---|---|---|
Tears | Saliva | Nasal mucus | Bronchial mucus | ||||
Lysozyme14 | ++++ | + | ++++ | ++++ | LYZ2 | 12 | |
Lactoferrin | ++++ | + | ++++ | ++++ | LACT3 | 3 | |
Tear lipocalin (VEGP) | ++++ | + | ? | +/−4 | LCN15 6 | 9q 34.3 | |
Secretory IgA14 | ++++ | +++ | ++++ | ||||
Immunoglobulin A | IGHA7 | 14q32.33 | |||||
Secretory component | SC or PIGR8 | 1q31-q42 | |||||
J chain | IGJ9 | 4q21 | |||||
Cystatin S14 | + | ++ | + | + | CST310 11 | 20p11.2 | |
Mucin | + | ++++ | ++++ | ++++ | MUC 112 | 1q21-24 | |
MUC5AC13 | 11p15 |