Table 3

Comparison between the effects of different concentrations of thiotepa and 5-FU on cell proliferation (cell count) at day 14

ThiotepaConcentration of thiotepa (mg/ml)
Control0.060.1250.251.04.0
(A) 5 minute exposure to thiotepa:
 Concentration of thiotepa (mg/ml)0.06
0.125
0.25
1.0
4.0
(B) 30 minute exposure to thiotepa:
 Concentration of thiotepa (mg/ml)0.06
0.125
0.25
1.0
4.0
Concentration of 5-FU (mg/ml)
5-FU Control 0.25 2.5 5.0 10.0 25.0
(C) 5 minute exposure to 5-FU:
 Concentration of 5-FU (mg/ml)0.25
2.5
5.0
10.0
25.0
(D) 30 minute expossure to 5-FU:
 Concentration of 5-FU (mg/ml)0.25
2.5
5.0
10.0
25.0
  • Denotes significant difference (p<0.05) between the two concentrations.