Table 2

Mean (SD) intensity of immunostaining of the retina/choroid using an anti-VEGF121,165,189antibody

Tissue layer
Tissue category Choroidal vessels RPE Outer retina Inner retina Retinal vessels Ganglion cell layer ILM
Normal (n=12)0.3 (0.1)0.5 (0.4)0.2 (0.1)0.2 (0.1)0.3 (0.1)0.4 (0.2)0.3 (0.2)
Diabetic:
No overt retinopathy (n=19)0.7 (0.2)1.3 (0.2)0.8 (0.2)1.6 (0.2)1.0 (0.2)1.9 (0.2)1.5 (0.2)
 Vascular abnormalities (n=6)0.5 (0.3)0.8 (0.4)0.3 (0.3)1.2 (0.5)1.1 (0.4)1.7 (0.4)1.3 (0.4)
 PDR (n=6)1.0 (0.5)1.8 (0.4)1.5 (0.4)1.8 (0.3)2.2 (0.3)2.0 (0.4)1.8 (0.4)
 Laser, no PDR (n=15)0.7 (0.2)1.2 (0.3)1.2 (0.3)1.1 (0.2)1.0 (0.2)1.2 (0.2)1.0 (0.2)
  • 0 = background, 1 = weak, 2 = moderate, 3 = intense.