Effect of endothelium removal on constrictor responses of bovine anterior ciliary arteries
| Maximum contraction (Emax) (mN/mm) | pD2 | ||||||
|---|---|---|---|---|---|---|---|
| Intact | Denuded | p Value | Intact | Denuded | p Value | ||
| 5-HT | 3.65 (0.25) (12) | 3.26 (0.27) (10) | 0.30 | 7.04 (0.08 (12)) | 7.07 (0.07) (10) | 0.84 | |
| NA | 2.78 (0.28) (9) | 2.64 (0.33) (9) | 0.75 | 6.70 (0.05) (9) | 6.62 (0.18) (9) | 0.54 | |
| PE | 3.18 (0.35) (8) | 2.45 (0.20) (7) | 0.10 | 4.64 (0.19) (8) | 4.54 (0.20) (7) | 0.73 | |
| PGF2α | 2.83 (0.31) (8) | 2.57 (0.44) (5) | 0.63 | 5.28 (0.12) (8) | 5.36 (0.22) (5) | 0.73 | |
| ET-1 | 4.21 (0.24) (9) | 3.67 (0.48) (10) | 0.34 | 8.17 (0.06) (9) | 8.26 (0.06) (10) | 0.36 | |
| KCl | 4.08 (0.31) (8) | 3.51 (0.39) (5) | 0.28 | 1.55 (0.03) (8) | 1.56 (0.05) (5) | 0.84 | |
Values are expressed as mean (SEM) (n). p Values comparing maximum contractions and pD2 values in endothelium intact versus denuded arteries.