Table 1

Effect of endothelium removal on constrictor responses of bovine anterior ciliary arteries

Maximum contraction (Emax) (mN/mm)pD2
IntactDenudedp ValueIntactDenudedp Value
5-HT3.65 (0.25) (12)3.26 (0.27) (10)0.307.04 (0.08 (12))7.07 (0.07) (10)0.84
NA2.78 (0.28) (9)2.64 (0.33) (9)0.756.70 (0.05) (9)6.62 (0.18) (9)0.54
PE3.18 (0.35) (8)2.45 (0.20) (7)0.104.64 (0.19) (8)4.54 (0.20) (7)0.73
PGF 2.83 (0.31) (8)2.57 (0.44) (5)0.635.28 (0.12) (8)5.36 (0.22) (5)0.73
ET-14.21 (0.24) (9)3.67 (0.48) (10)0.348.17 (0.06) (9)8.26 (0.06) (10)0.36
KCl4.08 (0.31) (8)3.51 (0.39) (5)0.281.55 (0.03) (8)1.56 (0.05) (5)0.84
  • Values are expressed as mean (SEM) (n). p Values comparing maximum contractions and pD2 values in endothelium intact versus denuded arteries.