Table 1

Clinical findings in 14 patients presenting with cellulitis associated with retinoblastoma

Case NoSex/age (months)
Eye
Clinical signs Temp (°C)WCC Medical treatmentOther treatmentCurrent status (months after presentation)
1F/12
Left
Oedematous C
IOP 43 mm Hg
36.516 400IV cefotaxime 500 mg 8;
IV prednisolone 5 mg 12
Enucleation
Adjunctive chemotherapy
Alive (48)
2F/30
Left
Quiet AC
IOP 40 mm Hg
36.516 400IV cefazolin 100 mg 6;
dexamethazone 5 mg, 1 dose
EnucleationAlive (50)
3F/12
Right
Quiet AC post seg haem,
IOP 17 mm Hg
37.512 000IV ampicillin 250 mg 6; IV flucloxacillin 250 mg 6. At local hospitalEnucleationAlive (113)
4M/16
Left
Oedematous C
IOP: NA
37.519 300IV flucloxacillin 500 mg 6;
Decadron 5 mg 8 × 72 hours
EBRT
Adjunctive chemotherapy
Alive (108)
5F/6
Left
Phthisis
IOP: NA
NANAIV antibiotics at local hospitalEnucleation
Adjunctive chemotherapy
Alive (35)
6M/24
Left
Opaque C, “fluffy material” in AC
IOP 24 mm Hg
36.012 200IV cefazolin 125 mg 6;
IV prednisolone 2.5 mg 6
Enucleation
Adjunctive chemotherapy
Alive (40)
7F/24
Right
Fibrin in AC
IOP high
37.517 200IV cefazolin 110 mg 6;
IV prednisolone 2.5 mg 6
EnucleationAlive (44)
8F/24
Right
Opaque C, shallow AC
IOP 50 mm Hg
38.015 000PO Cechlor 250 mg 6Enucleation
Adjunctive chemotherapy
Dead (78)
9F/7
Right
Hazy C
IOP 30 mm Hg
37.511 700IV ampicillin 200 mg 8;
IV prednisolone 2 mg 8
Enucleation
EBRT
Alive (40)
10F/20
Left
Cell and flare in AC
IOP: NA
NANANo treatmentEBRT
Enucleation
Alive (138)
11F/20
Left
Rubeosis iridis, shallow AC
IOP high
39.517 400IV Kefzol 30 mg 6;
IV gentamicin 15 mg 8
EBRT
Adjunctive chemotherapy
Dead (2o to disseminated Rb)
12M/14
Left
Opaque C
IOP: NA
37.415 200IV ampicillin 250 mg 6;
IV prednisolone 7.5 mg 6
Enucleation
EBRT
Adjunctive chemotherapy
Alive (31)
13 M/2
Right
Opaque C
IOP: NA
37.4 9 500IV prednisolone 1.0 mg 6 × 96 hours
IV prednisolone 2.0 mg 6 × 48 hours
EnucleationAlive (21)
14F/36
Left
Opaque C disorganised AC with
tumour
IOP: NA
3611 300IV prednisolone 2.5 mg 6 EnucleationAlive (9)
  • Cellulitic eyes only described.

  • AC=anterior chamber; EBRT=external beam radiation therapy; f/u=follow up; C=cornea; NA=not available; post seg=posterior segment; WCC=white cell count.