Table 3

Renal responses to cyclosporin A therapy

Patient NoMaint CsA dose (mg/kg)Max CsA dose (mg/kg)End serum creatinine (μmol/l)/ (End % from baseline)Normal serum creatinine for age/ (% above upper limit)
13.35.053 (2)30–76 (0)
2 4.2 5.3 89 (98) 29–85 (5)
34.85.041 (−16)23–73 (0)
41.45.061 (3)15–93 (0)
5 3.0 3.0 79 (119) 25–75 (5)
6 4.3 5.1 70 (32) 24–80 (0)
75.07.525 (14)23–63 (0)
8 4.0 5.5 75 (42) 23–73 (3)
93.66.088 (24)20–98 (0)
103.55.080 (13)27–97 (0)
114.75.080 (14)24–80 (0)
124.75.079 (5)30–80 (0)
134.85.178 (8)30–80 (0)
144.25.589 (6)21–109 (0)
  • Maint = maintenance; Max = maximum; CsA = cyclosporin A.

  • Figures are outlined in bold if the serum creatinine at the time of last visit had risen more than 30% from baseline.