Characteristics in relation to the stages of AMD
| Drusen (n=496) | Pigment epithelium alteration (n=333) | Geographic atrophy (n=343) | Exudative maculopathy (n=672) | |
|---|---|---|---|---|
| Age (years) | 71.1 | 72.1 | 74.8 | 74.0 |
| Sex (% women) | 73.2 | 66.4 | 72.0 | 66.2 |
| Drusen (%): | 99.6 | 77.2 | 72.6 | 54.6 |
| Small hard | 69.0 | 48.3 | 42.6 | 27.5 |
| Large hard | 88.9 | 64.0 | 63.0 | 47.2 |
| Soft | 54.8 | 27.9 | 26.8 | 12.1 |
| Soft and confluent | 31.5 | 10.5 | 10.2 | 5.5 |
| Pigment epithelium detachment | 2.8 | — | — | 15.5 |
| Pigmentation alterations: | ||||
| Hypopigmentation (%) | 27.2 | 94.3 | 13.4 | 11.9 |
| Involving the foveola | 5.4 | 35.4 | 3.8 | 4.0 |
| Macular, not involving the foveola | 16.5 | 82.6 | 8.7 | 9.1 |
| Extramacular | 26.0 | 89.5 | 12.5 | 10.9 |
| Hyperpigmentation (%) | 36.1 | 83.8 | 65.6 | 31.5 |
| Involving the foveola | 12.1 | 33.9 | 23.0 | 10.6 |
| Macular, not involving the foveola | 22.8 | 72.1 | 45.5 | 21.6 |
| Extramacular | 29.8 | 80.5 | 63.0 | 29.5 |
| Atrophy (%): | — | — | 98.5 | — |
| Involving the foveola | — | — | 67.6 | — |
| Macular, not involving the foveola | — | — | 91.5 | — |
| Extramacular | — | — | 96.5 | — |
| CNV (%): | — | — | — | 98.2 |
| Involving the foveola | — | — | — | 30.1 |
| Macular, not involving the foveola | — | — | — | 72.0 |