Analysed risk factors in the study population
| Total population | ||||
|---|---|---|---|---|
| Univariate analysis | Multivariate analysis OR (95% CI) | |||
| AMD No (%) | Controls No (%) | OR (95% CI) | ||
| Cardiovascular disease: | ||||
| Systemic hypertension | 760 (41.5) | 636 (34.8) | 1.33 (1.17–1.53) | 1.28 (1.09–1.50) |
| Coronary artery disease | 247 (13.5) | 168 (9.2) | 1.56 (1.26–1.93) | 1.31 (1.02–1.68) |
| Hypertension or coronary artery disease | 858 (47.0) | 708 (38.8) | 1.40 (1.22–1.60) | |
| Smoking (non-smoking): | 1298 (70.5) | 1341 (72.9) | ||
| Past | 340 (18.5) | 296 (16.1) | 1.24 (1.02–1.51) | 1.12 (0.90–1.41) |
| Present | 202 (11.0) | 203 (11.0) | 1.06 (0.84–1.33) | 1.09 (0.83–1.42) |
| Spherical equivalent (emmetropia): | 352 (23.3) | 419 (27.8) | ||
| Myopia | 252 (16.7) | 277 (18.4) | 1.08 (0.87–1.36) | 0.99 (0.78–1.25) |
| Hyperopia | 904 (59.9) | 812 (53.8) | 1.34 (1.12–1.59) | 1.33 (1.11–1.59) |
| Iris colour (dark): | 809 (44.4) | 869 (47.7) | ||
| Light (blue, green, grey) | 1013 (55.6) | 953 (52.3) | 1.15 (1.00–1.31) | 1.22 (1.05–1.42) |
| Lens (no lens opacities and no cataract surgery): | 728 (39.9) | 915 (50.2) | ||
| Lens opacities | 1002 (55.0) | 822 (45.1) | 1.69 (1.45–1.97) | |
| Cataract surgery | 93 (5.1) | 86 (4.7) | 1.53 (1.10–2.11) | |
| Lens opacities or previous cataract surgery | 1095 (60.1) | 908 (49.8) | 1.68 (1.45–1.95) | 1.55 (1.31–1.84) |
↵Reference group for polychotomous variables.