Table 2

Sensitivities and specificities of antigen detection techniques for the diagnosis of adenovirus, HSV, and chlamydial keratoconjunctivitis in comparison with cell culture isolation

Causative agentTest formatCommercial nameSensitivity (%)Specificity (%)Reference
AdenovirusEIACambridge Adenoclone80.6100 42
62.3100 43
Cambridge Adenoclone77100 44
Cambridge Adenoclone38100 45
Cambridge Adenoclone50.5100 46
ICSAS Adenotest54.797.1 46
IF79100 42
IDB85.392.2 47
6793 48
HSVIIF9773 49
DIFSyva Microtrak86100 50
EIAKodak Surecell37.581.3 51
Kodak Surecell 2780 52
DuPont Herpchek65100 53
2690 53
IF59100 53
C trachomatis DIFSyva Microtrak10099 54
10097.5 55
Syva Microtrak,5781 56
Syva Microtrak83.396.6 57
5298 29
10052 34
IPO5496 29
EIAAbbott Chlamydiazyme7197 56
Abbott Chlamydiazyme8899 58
Kodak Surecell 40100 59
92.6494.54 60
  • DIF=direct immunofluorescence; IPO=immunoperoxidase; EIA=enzyme immunoassay; IIF=indirect immunofluorescence; IF=immunofiltration; IC=immunochromatography; IDB=immune dot blot.

  • Compared with PCR.

  • Compared with clinical diagnosis.

  • Compared with DIF.