Variable | Before pilocarpine | After pilocarpine | Change | p Value |
---|---|---|---|---|
Wide angle group (n=30): | ||||
Age (years) | 70.42 (2.91) (63 to 85) | — | — | |
Total axial length (mm) | 24.91 (2.63) (21.46 to 28.76) | — | — | |
Lens thickness (mm) | 3.82 (0.68) (2.48 to 5.01) | — | — | |
ACD (μm) | 2963 (267) (2506 to 3510) | 2816 (262) (2392 to 3353) | −147 (19) (−114 to −190) | |
TIA (degree) | 41.86 (7.47) (25.72 to 53.77) | 38.42 (3.77) (29.84 to 45.54) | − 3.44 (4.82) (−12.31 to +5.40) | |
AOD250 (μm) | 338.1 (70.6) (243 to 508) | 307.5 (42.9) (240 to 404) | − 30.6 (38.2) (−104 to +53) | |
AOD500 (μm) | 426.3 (73.8) (285 to 564) | 392.0 (42.9) (305 to 468) | − 34.3 (40.7) (− 127 to +32) | |
Iris thickness (μm) | 464.8 (69.6) (395 to 602) | 358.3 (68.0) (270 to 418) | −106.5 (30.6) (−187 to −50) | |
ILCD (μm) | 1,223 (657) (856 to 1,765) | 2,137 (433) (1,876 to 2,675) | 914 (543 (532) to 1,451) | |
ILCA (mm3) | 20.512(7.833) (14.128 to 29.325) | 37.435 (3.357) (33.699 to 44.747) | 16.923 (5.795) (7.483 to 23.619) | |
Narrow angle group (n=30): | ||||
Age (years) | 71.56 (2.76) (65 to 85) | — | — | 0.2498 |
Total axial length (mm) | 22.46 (1.00) (21.33 to 24.22) | — | — | 0.0017 |
Lens thickness (mm) | 4.88 (0.40) (4.38 to 5.46) | — | — | 0.0001 |
ACD (μm) | 2055 (214) (1706 to 2470) | 1961 (202) (1623 to 2360) | − 94 (15) (−67 to −120) | 0.0001 |
TIA (degree) | 16.79 (7.751) (3.32 to 30.22) | 24.73 (5.75) (14.79 to 34.11) | +7.94 (2.77) (+2.41 to +13.21) | 0.0001 |
AOD250 (μm) | 144.8 (69.8) (32 to 278) | 216.5 (48.9) (130 to 315) | +71.7 (29.1) (+13 to +120) | 0.0001 |
AOD500 (μm) | 195.7 (90.3) (49 to 367) | 278.7 (61.8) (181 to 382) | + 83.0 (37.2) (+7 to +142) | 0.0001 |
Iris thickness (μm) | 459.2 (49.8) (228 to 449) | 318.8 (78.8) (228 to 440) | − 140.4 (26.3) (46 to 132) | 0.1253 |
ILCD (μm) | 1,856 (534) (1,356 to 2,165) | 2,721 (378) (2,034 to 3,432) | 865 (467 (676) to 1,243) | 0.3747 |
ILCA (mm3) | 35.002 (7.203) (23.656 to 44.103) | 45.638 (7.686) (30.874 to 60.693) | 10.626 (7.585) (4.829 to 18.367) | 0.0006 |
Values are means (SD) examined by Student’st test and Welch’st test. ACD=anterior chamber distance; TIA=trabecular-iris angle; AOD250 and AOD500=angle opening distance at 250 μm and 500 μm from the scleral spur; ILCD and ILCA=iris-lens contact distance and area.