Table 1

Monoclonal antibody (mAb) specificity

mAbSpecificityReference
F4/80Blood monocytes, macrophages and some DC 10
SER4Sialic acid receptor on some macrophages 22
M5/114MHC class II (Ia) 23
B7-1 CD80, costimulatory molecule on APCs, ligand for CD28, and CTLA-4 24
B7-2CD86, costimulatory molecule on APCs, ligand for CD28, and CTLA-4
NLDC-145Non-lymphoid DC in skin, lymph, and interdigitating cells 25
M342Antigen within multivesicular bodies in mature DC associated with antigen processing 21
N418β2 (CD11c) intigrin on isolated splenic DC and some mature DC populations in other tissues 20