Table 1

Autosomal dominant cataract loci

PhenotypeLocusMutated gene (if known)Reference
Volkmann (pulverulent)1p3624
Posterior polar 1p3614
Zonular pulverulent1q21-25Connexin50 23, 46
Coppock-like (nuclear)2q33-36γ crystallin17, 30
Polymorphic (lamellar)2q33-3647
Total10q24-25Pitx348
Pulverulent 13q9
Marner (pulverulent)16q22.125
Anterior polar 17p1313
Zonular-sutural (lamellar)17q11-1249
Cerulean17q2427
Zonular central nuclear21q22.3α crystallin33
Cerulean22q11.2β crystallin28
  • Linkage first described by this study group.

  • Mutation first described by this study group.