Effects of placebo (physiological saline solution) or stepwise increasing doses of sodium nitroprusside, or phenylephrine on systolic and diastolic blood pressure and pulse rate. Data are presented as means (SEM) (n=9)
| Systolic blood pressure (mm Hg) | Diastolic blood pressure (mm Hg) | Pulse rate (beats/min) | |
|---|---|---|---|
| Placebo day | |||
| Baseline | 114.5 (9.2) | 60.9 (7.4) | 70.7 (10.3) |
| Syringe 1 | 113.4 (7.6) | 61.1 (5.4) | 68.6 (11.6) |
| Syringe 2 | 112.9 (3.3) | 60.6 (6.5) | 67.3 (8.8) |
| Syringe 3 | 109.6 (11.1) | 59.9 (6.9) | 67.2 (10.6) |
| Phenylephrine | |||
| Baseline | 113.8 (8.5) | 57.8 (9.2) | 61.2 (5.9) |
| 0.5 μg/kg/min | 121.0 (9.2) | 62.5 (10.9) | 59.2 (9.5) |
| 1.0 μg/kg/min | 132.5 (11.0) | 69.1 (10.4) | 48.9 (8.3) |
| 2.0 μg/kg/min | 145.4 (12.6) | 81.5 (11.1) | 45.6 (7.6) |
| Sodium nitroprusside | |||
| Baseline | 113.7 (8.4) | 61.2 (5.9) | 70.8 (6.1) |
| 0.5 μg/kg/min | 101.5 (11.9) | 59.2 (9.5) | 71.6 (6.8) |
| 1.0 μg/kg/min | 98.9 (9.7) | 48.9 (8.3) | 80.1 (12.7) |
| 2.0 μg/kg/min | 96.6 (6.5) | 45.6 ( 7.6) | 83.0 (6.7) |