Table 1

Clinical details and tumour size, location, cell type, growth fraction, telomerase activity, and hTR expression of the uveal melanomas examined

Case Age Location Size (mm) Cell type Degree of pigmentation Outcome MIB 1 (%) ISH hTR TRAP assay (rTA units)
161anterior equator12×10×3mixed, spindle epithelioidstrongawm10++40
271orbit28×27×22mixed, spindle epithelioid (original tumour, spindle)moderated10+++35
362anterior16×14×11mixed, spindle epithelioidmoderate strongawm20++20
473anterior equator12×12×11mixed, spindle epithelioidmoderateawm15++30
565equator12×11×11mixed, spindle epithelioidmildd15++35
671equator12×9×12mixed, spindle epithelioidmilda5++35
743equator14×12×11mixed, spindle epithelioidmoderated5++35
850anterior9×8×2mixed, spindle epithelioidmilda5+25
931anterior18×12×7mixed, spindle epithelioidmoderatea10++
1087anterior posterior23×17×12mixed, spindle epithelioidmoderatea10++
1155anterior18×15×11mixed, spindle epithelioidmoderatea10++
1233equator17×10×10spindlemildd10+
1381posterior12×10×5spindlemildawm5++
1454posterior15×10×15mixed, spindle epithelioidmildd10++

  • ↵a = alive without metastases; awm = alive with metastases; d = dead.

  • ↵Intensity of telomerase signal in hTR: + = mild, ++ = moderate, +++ = strong, ++++ = intense.