Summary of reported drug induced ocular reactions
| Drug | Reaction | Comments |
|---|---|---|
| amiodarone | optic neuropathy | sudden visual loss |
| chlorothiazide | oculomotor nerve palsy | |
| indapamide | cataract | bilateral |
| chlorpropamide | optic neuropathy | visual loss |
| glibenclamide | (1) myopia, (2) hyperopia, (3) lens changes | vision returned to normal on stopping therapy |
| interferon | retinopathy | mostly asymptomatic |
| streptokinase | retinal/vitreous haemorrhage | marked reduction in vision |
| warfarin | vitreous haemorrhage | blindness |
| erythropoietin | visual hallucinations | mechanism uncertain |
| isoniazid | optic neuropathy | vision normalised after stopping |
| ethambutol | optic neuropathy | |
| phenformin + ethanol | blindness | secondary to lactic acidosis following drinking binge |
| oral contraceptive | (1) diabetic retinopathy, (2) colour vision disturbance | (1) no adverse effect (2) mechanism uncertain |
| phenothiazines | cataracts | large study−strong association |
| allopurinol | cataracts | risk independent of diabetes in one study but significant factor in another |
| cidofovir | iritis + hypotony | iritis more likely in diabetes |
| scopolamine | acute angle glaucoma | predictable from transdermal patch |
| steroids (oral) | open angle glaucoma and ocular hypertension | large study confirmed increased risk |
| steroids (oral) | cataracts | increased risk |
| steroids (eye drops) | cataracts | small study but significant risk |
| steroids (inhaled) | cataracts | increased risk |
| OKT3 | reduced visual acuity | uncertain mechanism |