Table 2

Sensitivity and specificity of PCR, IHC, culture, and ISH for the detection of HSV-1. Strong PCR refers to at least 50 genome equivalents in sample before amplification and strong IHC indicates a strong IHC signal

Test Sensitivity (%) Specificity (%)
PCR82 78
IHC74 85
Both PCR and IHC+ve68 97
Culture 2100
In situ (LAT) 0
Strong PCR 28100
Strong IHC54 88
Either PCR or IHC+ve95 63
  • LAT = latency associated transcript.