Table 3

Relation of tumour characteristics to metastases and VEGF

Metastasis Mean VEGF
Cell type
 Spindle3/17 (17.6%)2.11
 Mixed8/21 (38.1%)2.04
 Epithelioid5/5 (100%)3.8
Size
 Small3/20 (15%)2
 Medium10/17 (58.8)2.16
 Large3/6 (50%)3.33
Mitoses
  0–9 per 20 hpf9/32 (28.2%)2.29
 >10 per 20 hpf7/11 (63.6%)2.15
Necrosis
 Absent9/26 (34.6%)1.81
 Present7/17 (41.2)2.85
Pigmentation
 Minimal6/21 (28.6%)2.86
 Moderate7/11 (63.4%)1.67
 Marked3/11 (27.3%)1.91
Microvascular pattern
 Other6/28 (21.4%)1.93
 Loop/networks10/14 (71.4%)2.78
Microvascular density
 <75/mm2 1/14 (7.1%)2
 75–150/mm2 7/13 (53.8%)2.46
 150–225/mm2 3/4 (75.0%)1.71
 >225/mm2 5/12 (41.7%)4.85
  • Correlation with metastasis.

  • Correlation with VEGF.