Clinical characteristics of type 1 and type 2 diabetic patients
| Type 1 diabetes (n = 1796) | Type 2 diabetes (n = 1563) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| R0–I | RII–IV | RV | R0–I | RII–IV | RV | ||||||
| without MP | with MP | without MP | with MP | ||||||||
| No of patients | 1101 | 406 | 269 | 20 | 869 | 320 | 362 | 12 | |||
| Age (years) | 28.3 (0.4) | 44.3 (0.6) | 46.6 (0.8) | 48.2 (2.6) | 59.2 (0.4) | 61.1 (0.5) | 62.1 (0.4) | 71.2 (3.1) | |||
| Diabetes duration (years) | 9.1 (0.2) | 26.6 (0.5) | 25.1 (0.6) | 33.2 (1.5) | 9.4 (0.2) | 16.1 (0.4) | 17.6 (0.3) | 19.3 (2.9) | |||
| Age at manifestation (years) | 19.8 (0.4) | 18.2 (0.6) | 21.7 (0.8)** | 15.4 (2.9) | 50.3 (0.4) | 45.5 (0.6) | 44.7 (0.5) | 51.8 (5.1) | |||
| BMI (kg/m2) | 23.4 (0.1) | 25.3 (0.2) | 25.8 (0.3) | 25.3 (0.8) | 30.0 (0.2) | 30.2 (0.3) | 30.2 (0.3) | 29.1 (1.0) | |||
| AER (μg/min) | 23.0 (3.1) | 131.4 (16.2) | 126.3 (18.2) | 286.1 (128.1) | 69.4 (6.6) | 208.7 (30.0) | 224.8 (22.9) | 247.8 (99.1) | |||
| Creatinine (μmol/l) | 73.3 (0.7) | 88.0 (2.6) | 99.4 (4.5)** | 139.5 (29.8) | 82.8 (0.9) | 100.3 (4.3) | 101.4 (2.9) | 108.4 (13.4) | |||
| Tg (mmol/l) | 1.5 (0.05) | 1.5 (0.05) | 1.9 (0.1) | 1.4 (0.1) | 3.3 (0.1) | 3.3 (0.2) | 3.1 (0.1) | 2.2 (0.2) | |||
| Cholesterol (mmol/l) | 5.2 (0.04) | 5.8 (0.06) | 6.2 (0.1)** | 5.7 (0.28) | 6.4 (0.06) | 6.5 (0.11) | 6.6 (0.10) | 6.4 (0.23) | |||
| HbA1c(%) | 8.7 (0.06) | 8.5 (0.08) | 8.6 (0.1) | 8.4 (0.31) | 9.2 (0.06) | 9.1 (0.10) | 9.3 (0.09) | 9.3 (0.51) | |||
Data represent means (SEM) and differences between RII–IV with maculopathy and RII–RIV without maculopathy (MP) significant at p <0.05 and p <0.01, respectively.
Significance **p <0.01;
↵p <0.05.
n = total number of patients in each cohort.