Table 2

Summary of the PED patients

PatientEyeAgeSexPrimary diagnosisPercentage of serumOther Rx tried in past Other Rx effective at same time Duration of PED (weeks)Size of PED (mm)Schirmer's <5 mmOutcomeTime of healing for successes (weeks)Time of cessation for failures (weeks)Reason for failure and other relevant diagnoses
1R41MDiabetic neurotrophic keratitis100SR, PSC, P41 × 1NoS1
1LDiabetic neurotrophic keratitis100SR, PSC, P41 × 1YesF2Enlarging ulcers at 2 weeks
2R75FNeurotrophic HSV100BSR81 × 2.5NoS4
3L66FPost-HSK100SR, PSR, P44 × 4.5NoF8Slow progress
4L70FPost-infectious50SK, B249 × 9NoF10Slow progress
5R84FOCP100P41.5 × 1.0YesS3 days
5LOCP100P, SR47.0 × 5.5YesF3Microbial keratitis (coag−ve staphylococcus)
6R75FHZO50B × 2101.4 × 2.4NoS4
7L75MRA50AMT, P, SRP122 × 1YesS 8 Stitch abscess(microbe unknown)
8R17FVernal, post-infectious ulcer in graft50SK60.25 × 0.5NoS1
9L57MNeurotrophic HSV and post-PK for perforation50LTLT12.5 × 3.4YesF2Slow progress
10R51MOCP50AMT, P, SRP22 × 8YesS6
11R85MOCP50SR, PP66 × 3.2YesF2Increasing discomfort
12L81FPost-infectious, KCS50PP63 × 4.7YesS4Candida infectious crystalline keratopathy
13R86MPost-infectious, OCP50P, SRP17x8YesS4
  • B = botulinum induced ptosis, P = punctal occlusion, AMT = amniotic membrane transplant, SR = silicone rubber contact lens, SC = scleral contact lens, S = success, F = failure.

  • All patients were using lubricating ointment unless a therapeutic contact lens was used.

  • Diagnosis made at the same time as when epithelium was found to be healed.

  • Recurrent PED after three attempts at stopping serum. Each time the PED responded to recommencement of serum.

  • There was time limitation to treatment because patient was from overseas and lack of improvement at 2 weeks led to decision to perform a central tarsorrhaphy and abandon serum drops.