Summary of the PED patients
| Patient | Eye | Age | Sex | Primary diagnosis | Percentage of serum | Other Rx tried in past | Other Rx effective at same time | Duration of PED (weeks) | Size of PED (mm) | Schirmer's <5 mm | Outcome | Time of healing for successes (weeks) | Time of cessation for failures (weeks) | Reason for failure and other relevant diagnoses |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | R | 41 | M | Diabetic neurotrophic keratitis | 100 | SR, P | SC, P | 4 | 1 × 1 | No | S | 1 | ||
| 1 | L | Diabetic neurotrophic keratitis | 100 | SR, P | SC, P | 4 | 1 × 1 | Yes | F | 2 | Enlarging ulcers at 2 weeks | |||
| 2 | R | 75 | F | Neurotrophic HSV | 100 | B | SR | 8 | 1 × 2.5 | No | S | 4 | ||
| 3 | L | 66 | F | Post-HSK | 100 | SR, P | SR, P | 4 | 4 × 4.5 | No | F | 8 | Slow progress | |
| 4 | L | 70 | F | Post-infectious | 50 | SK, B | 24 | 9 × 9 | No | F | 10 | Slow progress | ||
| 5 | R | 84 | F | OCP | 100 | P | 4 | 1.5 × 1.0 | Yes | S | 3 days | |||
| 5 | L | OCP | 100 | P, SR | 4 | 7.0 × 5.5 | Yes | F | 3 | Microbial keratitis (coag−ve staphylococcus) | ||||
| 6 | R | 75 | F | HZO | 50 | B × 2 | 10 | 1.4 × 2.4 | No | S | 4 | |||
| 7 | L | 75 | M | RA | 50 | AMT, P, SR | P | 12 | 2 × 1 | Yes | S | 8 | Stitch abscess(microbe unknown) | |
| 8 | R | 17 | F | Vernal, post-infectious ulcer in graft | 50 | SK | 6 | 0.25 × 0.5 | No | S | 1 | |||
| 9 | L | 57 | M | Neurotrophic HSV and post-PK for perforation | 50 | LT | LT | 1 | 2.5 × 3.4 | Yes | F | 2 | Slow progress | |
| 10 | R | 51 | M | OCP | 50 | AMT, P, SR | P | 2 | 2 × 8 | Yes | S | 6 | ||
| 11 | R | 85 | M | OCP | 50 | SR, P | P | 6 | 6 × 3.2 | Yes | F | 2 | Increasing discomfort | |
| 12 | L | 81 | F | Post-infectious, KCS | 50 | P | P | 6 | 3 × 4.7 | Yes | S | 4 | Candida infectious crystalline keratopathy | |
| 13 | R | 86 | M | Post-infectious, OCP | 50 | P, SR | P | 1 | 7x8 | Yes | S | 4 |
B = botulinum induced ptosis, P = punctal occlusion, AMT = amniotic membrane transplant, SR = silicone rubber contact lens, SC = scleral contact lens, S = success, F = failure.
↵All patients were using lubricating ointment unless a therapeutic contact lens was used.
↵Diagnosis made at the same time as when epithelium was found to be healed.
↵Recurrent PED after three attempts at stopping serum. Each time the PED responded to recommencement of serum.
↵There was time limitation to treatment because patient was from overseas and lack of improvement at 2 weeks led to decision to perform a central tarsorrhaphy and abandon serum drops.