Patient | Eye | Age | Sex | Primary condition | Serum % | Subj | RB1 | Fluo2 | Subj 1 month | RB1 1 month | Fluo2 1 month | Subj 2 months | RB1 2 months | Duration of use | Side effects | Other Rx at same time | Other Rx previouslya |
1 | R | 52 | F | Linear IgA | 50 | 4 | 8 | 8 | 3 weeks | Itch, pain and discharge | V, H | ||||||
2 | R | 79 | F | OCP | 100 | 4 | 14 | 13 | 1 | 3 | 5 | 1 | 2b | 7 months | Allergic to CAP | H | |
3 | R | 52 | F | OCP | 100 | 4 | 4 | 6 | 2 | 3 | 5 | 2 | 4 | 2 month | H | ||
3 | L | OCP | 100 | 4 | 12 | 11 | 2 | 7 | 10 | 2 | 4 | 2 month | H | ||||
4 | R | 55 | F | Sjøgren | 50 | 3 | 9 | 8 | 1 day | Small peripheral sterile infiltrate with overlying defect | |||||||
5 | R | 73 | F | Sjøgren | 50 | 4 | 16 | 12 | 1 week | Swelling and redness | V, A | ||||||
6 | R | 69 | F | Sjøgren | 50 | 4 | 12 | 7 | 3 | 12 | 5 | 3 | 8 | 2 months | |||
7 | R | 55 | F | Sjøgren | 50 | 4 | 8 | 9 | 1 | 3 | 6 | 1 month | H, SC, SR | ||||
8 | R | 45 | F | SJS | 50 | 4 | 10 | 14 | 2 | 7 | 6 | 2 | 6b | 3 months | SR | ||
9 | R | 41 | M | SJS | 50 | 2 | 6 | 5 | 2 | 6 | 5 | 2 weeks | A | ||||
9 | L | SJS | 50 | 2 | 9 | 4 | 2 | 9 | 11 | 2 weeks | A |
a = All patients had puncti occluded and were on 10 minute to 2 hourly hypromellose or saline (without preservative) drops and twice to four times daily ointment. b = continued drops for more than 2 months. 1 = National Eye Institute Rose Bengal scoring system (0–18). 2 = National Eye Institute Fluorescein scoring system (0–15). RB = rose bengal score, Fluo = fluorescein score, Subj = subjective score, Rx = treatment, V = viscotears, A = acetylcysteine, H = hyaluronic acid (Healon), SC = scleral contact lens, SR = silicone rubber contact lens. OCP = ocular cicatricial pemphigoid, SJS = Stevens-Johnson syndrome, CAP = chloramphenicol.
↵Patients felt worse and stopped serum drops. They were not available for review at time of discomfort while they were still on serum. At time of review a week or more later the findings were the same as the pretreatment parameters.