Table 3

Comparative estimates of the MMP content of the granulocytes, monocytes, and blood plasma of healthy subjects and patients with rheumatoid arthritis

Zymographic activity/unit protein
MMPRheumatoid patients (n=8)Healthy subjects
(n=5)
p value
Granulocytes
Mr 116 0000.74 (0.22)0.92 (0.40)>0.2
 MMP-92.36 (0.47)2.58 (0.54)>0.2
 MMP-20.04 (0.05)0.30 (0.16)<0.001
Monocytes
Mr 116 0000.03 (0.04)0.02 (0.04)>0.2
 MMP-90.96 (0.80)2.42 (0.72)0.007
 MMP-20.31 (0.16)0.50 (0.10)0.04
Blood plasma
Mr 116 0000.11 (0.12)0.12 (0.04)>0.2
 MMP-90.18 (0.14)0.14 (0.05)0.06
 MMP-20.95 (0.17)0.90 (0.17)0.06
  • Values are mean (SD).