Table 1

A comparison of the clinical features of 169 consecutive eyes with iris melanoma with and without secondary elevated intraocular pressure (IOP)

Eyes with elevated IOP (n=50) Eyes without elevated IOP (n=169)
Patient age (years)
 mean (median, range)46 (53, 7–90)41 (41, 8–87)
Visual acuity
 20/20–20/4032 (64%)112 (94%)
 20/50–20/10010 (20%)6 (5%)
 20/200 or worse6 (12%)1 (<1%)
 unavailable2 (4%)0
Iris colour
 blue43 (86%)100 (84%)
 green7 (14%)10 (8%)
 brown0 (0%)9 (8%)
Intraocular pressure (mm Hg)
 mean (median, range)33 (31, 23–65)15 (15, 9–22)
Tumour size (No of clock hours)
 mean (median, range)5 (4, 1–12)3 (2, 1–12)
Tumour base (mm)
 mean (median, range)7 (6, 1–13)6 (5, 1–12)
Tumour thickness (mm)
 mean (median, range)2 (2, 1–4)2 (2, 1–4)
Tumour configuration
 nodule23 (46%)98 (82%)
 flat27 (54%)21 (18%)
Tumour colour
 brown39 (78%)85 (71%)
 yellow11 (22%)34 (28%)
Tumour seeding iris (No of clock hours)
 mean (median, range)6 (6, 0–12)3 (0, 0–12)
Tumour seeding angle (No of clock hours)
 mean (median, range)7 (7, 0–12)3 (1, 0–12)
Associated findings
 ectropion iridis23 (46%)52 (44%)
 corectopia29 (58%)75 (63%)
 prominent episcleral vessel17 (34%)26 (22%)
 feeding tumour vessel13 (26%)29 (24%)
 intrinsic tumour vessel17 (34%)55 (46%)
 hyphaema4 (8%)12 (10%)
 cell and flare3 (6%)4 (3%)
 secondary cataract5 (10%)18 (15%)
Tumour management
 enucleation30 (60%)21 (18%)
 local resection 11 (22%)91 (76%)
 plaque radiotherapy5 (10%)4 (3%)
 observation 4 (8%)3 (2%)
  • Local resection = iridectomy, iridocyclectomy, or iridocyclogoniectomy.

  • Observation = in all cases the tumour was cytologically low grade and observation was patient's preference.