Table 9

Sensitivity analysis to evaluate the effect of quality of randomised controlled trials on IOP reduction between latanoprost and timolol

Difference in percentage IOP reduction 95% Confidence intervals
Design of trial
 All trials6.04.3, 7.8
 Double blind, parallel6.04.2, 7.8
 Double blind, crossover5.6−9.9, 21.1
 Single blind, parallel6.8−1.0, 14.7
 All trials6.04.3, 7.8
 Withdrawals ⩽10%5.43.3, 7.5
 Withdrawals >10%7.84.4, 11.2
  • All pooling was undertaken using fixed effect model as no heterogeneity was detected by Q test.