Table 1

Mean fluorescein concentrations (ng/ml) of cornea (C), anterior chamber (AC), and integral from corneal endothelium to anterior lens surface (AUC) over time after drop and lyophilisate application (n=12)

Cornea (C)Anterior chamber (AC)Area cornea-lens (AUC)
Time (minutes)DropLyophilisateDropLyophilisateDropLyophilisate
*Significant difference, p≤0.05.
08.257.453.582.601223.761168.97
1523,23772.88*7.6526.27*1405.937161.68*
3014.8978.804.406.11*1310.471749.74
4512.5023.22*4.406.64*1338.951469.35
6010.4120.88*5.187.98*1285.891426.35
12012.9415.81*5.5311.52*1394.211537.00
18010.2320.91*5.2413.12*1340.621686.18*