Table 1

Clinical features and histopathology of globes with diode laser cyclophotocoagulation

CaseAge/ sexCause of glaucomaType of treatmentTime of treatment prior to enucleationClinical response*Pars plicata injuryPars plana injuryOther complicationsPhthisisReason for enucleation
*Clinical response is measured as IOP (mm Hg); †15002 = 1500 mW × 1500 ms.CRVO = central retinal vein occlusion, PXF = pseudoexfoliation, PK = penetrating keratoplasty, PCIOL = posterior chamber intraocular lens, COAG = chronic open angle glaucoma, MM = malignant melanoma, Trab = trabeculectomy, ACIOL = anterior chamber intraocular lens.
1F/80Neovascular (CRVO)Diode 360° 40 × 1500 ms × 1500 mW8 monthsIOP 78→22 Late rise →48ModerateNot affectedNoPerforated microbial keratitis; high IOP
2F/64Absolute PXFDiode 360° 40 × 1500 ms × 1500 mW5 monthsIOP 44→19 IOP 34 @ 4 weeks IOP 50 @ 6 weeks IOP 40 @ 4 weeksModerate to severeSevereNoBlind, painful, high IOP
3F/64Epithelial downgrowth post PK ×2; sutured PCIOLDiode 180° 4–10 o'clock: 23 burns × 1500 ms × 1500 mW12 monthsIOP 56→10 Rise to 22–30 @ 4 monthsSevereMildNoRecurrent high IOP, rapidly enlarging cystic bleb
4M/65Chronic angle closure glaucoma after penetrating keratoplasty.Diode ×3 #1 270° 12–9 o'clock, 30 × 15002 † #2 180° 10–4 o'clock, 20 × 15002; #3 180° 3–9 o'clock, 2000 mW × 1500 ms2 years 1 month 1 year 7 months 11 months#1 no IOP change; #2 IOP 50→18, but PK failed, IOP→ 28 #3 IOP→17SevereSevereScleral damageNoPainful, with unresolved inferior herpes simplex virus keratitis (IOP controlled)
5M/71R COAGDiode 270° 3–12 o'clock 2200 mW × 18 shots7 monthsIOP 48→50 @ 3 and 4 monthsModerate to severeModerateNecrosis of iris base, apposed to angleNoHigh IOP Total hyphaema,-blood stained cornea
6M/44NeovascularDiode 270° 12–9 o'clock, 2000 ms × 1700–2000 mW4 monthsIOP 42→20; IOP increased again to 48 @ 4 monthsModerateNot affectedIris base necrosis Scleral damageNoBlind, painful, total retinal detachment
7M/74Neovascular post plaque for choroidal MM; failed L trab.Diode 180° 10–4 o'clock; 20 × 150024 years 1 monthIOP response poor; 40+ at enucleationMildNot affectedNoRecurrent inflammation?active tumour, blind painful eye
8F/31Neovascular, tractional retinal detachment (surgery including silicone oil), chronic uveitisDiode × 4 #1 inf 180° 22 × 15002 #2 lat 180° 20 × 15002 #3 3–12 o/clock 1510mW × 2100 ms #4 360° 1750–2000 ms × 1500–2000 mW#1 6 months #2 4 months #3 6 weeks #4 2 weeks#1 26→21 #2 45→38→16 #3 38→11→40 #4 40→21→14Moderate to severeMildIris necrosis; Scleral damageNoPersisting pain despite IOP control
9M/75R traumatic aphakia; epithelial downgrowth post 2° ACIOLDiode ×2 #1 Inf 180° 2000 mW × 1500 ms; #2 Nasal 180° 20002#1 7 months>br>#2 5 monthsIOP 42→16, but 35 @ 6 weeks; #2 Rx →IOP 14, 16Moderate to severeMildNoPersisting pain due to corneal decompensation despite IOP control