Scores for symptoms and global discomfort index (mean (SD)) of patients of both groups
Time (days) | Burning | Foreign body sensation | Dryness | Mucous discharge | Itching | Photophobia | Discomfort index |
---|---|---|---|---|---|---|---|
*p <0.001 v time 0 starting from day 15; †p = 0.0002 v time 0 starting from day 30; §p = 0.02 v group 2 patients at the same period of observation. | |||||||
Group 1: hypotonic 0.4% sodium hyaluronate | |||||||
0 | 2.4 (0.8) | 2.7 (0.5) | 2.4 (0.5) | 1.9 (0.5) | 1.3 (1.1) | 1 (0.8) | 11.7 (3.1) |
15 | 1.4 (0.5)* | 1.2 (0.8)* | 1.4 (0.9)* | 1 (0.8)* | 0.4 (0.5)* | 0.6 (0.5) | 6 (2.2)*§ |
30 | 0.5 (0.5) | 0.6 (0.5) | 0.3 (0.5) | 0.4 (0.5) | 0.2 (0.4) | 0.2 (0.4)† | 2.3 (1.4) |
90 | 0.3 (0.5) | 0.5 (0.5) | 0.2 (0.4) | 0.3 (0.5) | 0.1 (0.4) | 0.1 (0.3) | 1.6 (1.2) |
Group 2: isotonic 0.4% sodium hyaluronate | |||||||
0 | 2.2 (0.6) | 2.6 (0.5) | 2.4 (0.7) | 1.8 (0.4) | 1.3 (0.9) | 1 (0.6) | 11.4 (1.8) |
15 | 1.4 (0.8)* | 1.5 (0.7)* | 1.6 (0.8)* | 1.2 (0.6)* | 0.6 (0.5)* | 0.7 (0.6) | 7.5 (1.7)* |
30 | 0.7 (0.5) | 0.7 (0.5) | 0.4 (0.5) | 0.5 (0.5) | 0.3 (0.5) | 0.3 (0.5)† | 3 (1) |
90 | 0.5 (0.5) | 0.5 (0.5) | 0.3 (0.5) | 0.4 (0.5) | 0.2 (0.4) | 0.2 (0.4) | 2.1 (1) |