Serum homocysteine, endothelin-1, and nitric oxide levels in patients with Behçet's disease and controls with statistical comparisons
| All BD (n=43) | Active BD (n=20) | Inactive BD (n=23) | Ocular BD (n=27) | Non-ocular BD (n=16) | Control (n=25) | |
|---|---|---|---|---|---|---|
| Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | |
| BD, Behçet's disease; tHcy, total homocysteine; ET-1, endothelin-1; NO, nitric oxide. | ||||||
| *The mean age between the groups was comparable (p>0.05). | ||||||
| †Significantly different from the controls by Mann-Whitney U test (for each, p<0.001). | ||||||
| ‡Significantly different from the inactives (Wilcoxon test; for each, p<0.05) and controls (Mann-Whitney U test; for each, p<0.001). | ||||||
| §Significantly different from the non-ocular patients (Wilcoxon test; for each, p<0.01) and controls (Mann-Whitney U test; for each, p<0.001). | ||||||
| Age (years)* | 36.95 (9.80) | 37.35 (9.39) | 36.60 (10.34) | 38.80 (9.84) | 35.18 (9.65) | 37.88 (8.73) |
| tHcy (ng/ml) | 15.83 (4.44)† | 17.79 (3.90)‡ | 14.13 (4.23) | 18.25 (4.20)§ | 13.53 (3.34) | 7.96 (2.66) |
| ET-1 (μmol/ml) | 17.47 (4.33)† | 19.17 (3.71)‡ | 15.99 (4.35) | 19.40 (5.02)§ | 15.62 (2.48) | 5.74 (2.34) |
| NO (μmol/l) | 37.60 (10.31)† | 41.15 (7.96)‡ | 34.52 (10.76) | 42.00 (10.62)§ | 33.40 (7.48) | 27.08 (7.76) |