Description of cases and controls and univariate associations
| Cases (n = 15479) | Controls (n = 15479) | Odds ratio (95% CI) | |
|---|---|---|---|
| *Matching variables so no odds ratios given. | |||
| Number (%) female* | 10006 (64.6) | 10006 (64.6) | |
| Mean age (years) (SD)* | 75.0 (10.0) | 75.0 (10.0) | |
| Mean observation period (years) (SD)* | 4.5 (2.6) | 4.5 (2.6) | |
| Mean annual consultation rate: | |||
| <2 | 1898 (12.3%) | 4733 (30.6%) | Baseline |
| 2 to <5 | 4467 (28.9%) | 4446 (28.7%) | 2.83 (2.63 to 3.05) |
| 5 to <8 | 3879 (25.1%) | 3029 (19.6%) | 3.85 (3.56 to 4.16) |
| ⩾8 | 5235 (33.8%) | 3271 (21.1%) | 5.06 (4.67 to 5.49) |
| BMI: | |||
| 15- | 2189 (14.1%) | 1718 (11.1%) | Baseline |
| 22- | 3022 (19.5%) | 2589 (16.7%) | 0.93 (0.85 to 1.01) |
| 25- | 2819 (18.2%) | 2446 (15.8%) | 0.92 (0.84 to 1.00) |
| 28- | 2938 (19.0%) | 2486 (16.1%) | 0.95 (0.87 to 1.03) |
| Missing data | 4511 (29.1%) | 6240 (40.3%) | |
| Smoking status: | |||
| Non-smoker | 9131 (59.0%) | 7801 (50.4%) | Baseline |
| Ex-smoker | 2040 (13.2%) | 1711 (11.1%) | 1.03 (0.96 to 1.11) |
| Current smoker | 2272 (14.7%) | 2082 (13.5%) | 0.96 (0.89 to 1.03) |
| Missing data | 2036 (13.2%) | 3885 (25.1%) | |
| Diabetes | 1735 (11.2) | 790 (5.1) | 2.37 (2.17 to 2.59) |
| Hypertension | 5028 (32.5) | 4235 (27.4) | 1.29 (1.23 to 1.35) |
| Glaucoma | 1125 (7.3) | 577 (3.7) | 2.03 (1.83 to 2.25) |
| Asthma | 1789 (11.6%) | 1234 (8.0%) | 1.52 (1.41 to 1.65) |
| COPD | 1269 (8.2%) | 887 (5.7%) | 1.49 (1.36 to 1.63) |