Pericyte coverage index (PCI; %) of pathological corneal blood vessels in vascularised human corneas with different duration of corneal neovascularisation (CN) as detected using electron microscopy (n=15)
| Electron microscopy | ||||
|---|---|---|---|---|
| Corneal disease | Duration of CN (months)* | PCI of capillaries (n)† | PCI of precapillary and postcapillary vessels (n)† | PCI of all vessels (n)† |
| *CN = pathological corneal neovascularisation; †percentage of vessels with pericyte coverage (in parentheses the number of vessels analysed for this cornea is given); ‡not unequivocally detectable; §corneas with clinically ongoing angiogenesis. | ||||
| Bullous keratopathy | –‡ | 50 (8) | 82 (11) | 68 (19) |
| Trauma | 0.5 | 88 (8) | 81 (21) | 83 (29) |
| Ocular pemphigoid | 3 | – | 100 (2) | 100 (2) |
| Peripheral ulcer in PCP | 3 | 27 (11) | 82 (17) | 61 (28) |
| Transplant insufficiency | 3 | 100 (3) | 100 (7) | 100 (10) |
| Transplant insufficiency | 11 | 100 (2) | 100 (3) | 100 (5) |
| Transplant insufficiency§ | 36 | 100 (2) | 95 (19) | 95 (21) |
| Transplant insufficiency§ | 60 | 50 (2) | 100 (9) | 91 (11) |
| Herpetic keratitis | 60 | 100 (2) | 100 (9) | 100 (11) |
| Herpetic keratitis§ | 60 | 100 (5) | 83 (6) | 91 (11) |
| Herpetic keratitis§ | 72 | 83 (6) | 100 (1) | 86 (7) |
| Herpetic keratitis | 72 | 100 (8) | 100 (5) | 100 (13) |
| Herpetic keratitis | 96 | – | – | – |
| Aniridia | 204 | 100 (14) | 100 (8) | 100 (22) |
| Herpetic keratitis | 360 | 100 (2) | 100 (5) | 100 (7) |
| Mean (SD) | 73 (95) | 91 (13) (196) | ||