Distribution of α1–6(IV) collagen in Bruch’s membrane and choroid of human globes detected with isoform specific anti-collagen IV monoclonal antibodies
| Isoform | α1(IV) | α2(IV) | α3(IV) | α4(IV) | α5(IV) | α6(IV) |
|---|---|---|---|---|---|---|
| Using Fisher’s exact test, when seen, the expression of the collagen IV isoforms was significant, with p<0.00001 except α3(IV)–α5(IV) in the choriocapillaris BM where p=0.045 | ||||||
| RPE BM | 10 | 10 | 13 | 13 | 13 | 0 |
| CC BM | 18 | 18 | 5 | 5 | 5 | 0 |
| BV (choroid) | 18 | 18 | 0 | 0 | 0 | 0 |