Table 2

Description of eyes affected by corneal calcification after amniotic membrane grafting

PatientEyePrimary diagnosisSecondary diagnosisAgeSexLength of FU (weeks)Graft technique*No of AMT before Ca2+No of retreatmentsRisk factorsOther previous surgery†Latest status
AMT = amniotic membrane transplant, FU = follow up, HSV = herpes simplex virus, *graft technique S = sandwich (graft and patch), G = inlay graft, †previous other surgery; PKP = penetrating keratoplasty, ECCE = extracapsular cataract extraction, ICCE = intracapsular cataract extraction, IOL = intraocular lens, F = female, M = male.
CP = calcium noted preoperatively, CO = calcium noted other eye, CS = raised serum calcium, D = dry eye, P = phosphate containing drop given postoperatively, A = vitamin A ointment given postoperatively, S = severe ocular surface disease (included ocular pemphigoid or Fuchs-Stevens-Johnson disease)
1LHSV78F302 layer S00P, APKPConjunctival flap to cover defect and calcium
2LAcanthamoebaSecondary glaucoma37F472 layer G20PECCE (no IOL)Calcified cornea, comfortable in bandage contact lens
3RHSVNeuropathic cornea51M323 layer S02D, P, A2nd PKPHLA matched PKP
2nd with ECCEStill clear at 12 weeks
4LFuchs-Stevens-Johnsons syndromeSymblepheron68F642 layer G00CP, P, SCalcified with no epithelial defect
5RHSVNon-healing corneal defect in graft75F612 layer S00CS, P, APKPCalcified cornea with punctate staining
ICCE with scleral fixated lens
6LHSVBacterial ulcer47F275 layer G01P, AResidual calcium, HLA matched PKP, still clear at 12 weeks
7RSystemic graft versus host diseaseAbsolute dry eye34M152 layer G00CO, D, PECCEHuge plaque of calcium. Died before further treatment
8RPemphigoidSymblepheron85M333 layer S02CO, P, SNo recurrence of Ca2+ at 6 weeks
8LPemphigoidSymblepheron85M232 layer S01CO, CP, SEpithelialized cornea, no recurrence of Ca2+
9LThermal burn to corneaNon-healing defect in graft45F322 layer S00CP, PPKPCalcification off axis, but epithelial defect has recurred elsewhere