Adjusted hazard rate ratios for risk of therapy failure and therapy discontinuation*
| Adjusted hazard ratio | 95% CI | p Value | |
|---|---|---|---|
| *Hazard rate ratios and 95% confidence intervals (CIs) from adjusted Cox regression models. | |||
| †Reference group. | |||
| Therapy failure | |||
| Latanoprost† | 1.00 | ||
| Timolol | 1.95 | 1.60 to 2.38 | 0.005 |
| Other β blockers | 2.28 | 1.88 to 2.77 | 0.004 |
| Carbonic anhydrase inhibitors | 3.60 | 2.92 to 4.44 | <0.0001 |
| Miotics | 3.84 | 2.96 to 4.98 | <0.0001 |
| Sympathomimetics | 4.29 | 3.45 to 5.34 | <0.0001 |
| Therapy discontinuation | |||
| Latanoprost† | 1.00 | ||
| Timolol | 1.37 | 1.06 to 1.78 | 0.05 |
| Other β blockers | 1.49 | 1.07 to 2.07 | 0.01 |
| Carbonic anhydrase inhibitors | 2.52 | 1.16 to 5.44 | <0.0001 |
| Miotics | 3.08 | 1.20 to 7.88 | <0.0001 |
| Sympathomimetics | 2.45 | 1.16 to 5.19 | <0.0001 |