Table 2

 Parameters that have to be defined in the production of serum eye drops and previously described variations, storage, and application

Production factorPublished variations
rpm, rounds per minute; g, g force; BSS, balanced salt solution.
Clotting phase0–2 days
Centrifugal force1500 rpm (ca 300 g) to 4000 g (ca 5000 rpm)
Duration of centrifugation5–20 minutes
Dilution20%, 33%, 50%, or 100%
Diluent0.9% NaCl, BSS, 0.5% chloramphenicol eye drops
Container1–6 ml in insulin syringe or dropper bottle
Storage−20° to +4° C
Number of daily applications3 times to hourly