Table 1

Part A: Fluorescein concentrations (ng/ml) in the cornea and anterior chamber

Time (minutes)	Cornea					Anterior chamber
	Lyophilisate		Eye drops		p Value	Lyophilisate		Eye drops		p Value
	Mean	SD	Mean	SD		Mean	SD	Mean	SD
0	12.55	3.53	11.33	2.63	<0.483	6.25	2.84	5.35	1.96	<0.554
2	3390.99	2251.64	839.13	600.23	<0.009	73.75	43.63	22.67	12.33	<0.007
4	3058.79	1759.88	400.44	303.05	<0.001	61.18	29.90	14.59	9.53	<0.000
6	2874.19	2030.96	246.88	267.44	<0.002	69.96	58.94	10.25	5.51	<0.008
8	2007.50	1352.46	158.97	232.19	<0.001	48.97	36.39	9.67	5.83	<0.005
10	2033.17	2339.72	125.45	208.37	<0.023	44.92	39.94	8.84	6.46	<0.013
12	1768.04	2034.01	107.24	213.27	<0.033	46.35	49.76	8.01	4.84	<0.056
14	1312.99	1526.67	81.75	163.39	<0.023	37.82	44.66	6.93	2.97	<0.048
16	850.64	1020.11	74.49	154.55	<0.027	22.93	21.28	6.98	2.86	<0.041
18	1076.96	1350.76	61.72	123.14	<0.034	31.34	33.36	6.85	3.20	<0.041
20	701.75	898.02	46.95	77.99	<0.039	21.71	21.95	6.67	2.62	<0.056
22	669.74	902.55	51.10	83.78	<0.054	20.67	19.87	7.09	3.14	<0.070
24	554.47	706.71	39.91	66.99	<0.041	17.85	16.18	6.50	2.66	<0.060
26	339.59	407.39	44.83	77.51	<0.033	14.06	11.78	6.58	2.44	<0.087
28	246.19	318.75	45.43	72.32	<0.047	11.61	8.12	7.47	3.04	<0.190
30	160.50	219.39	32.98	42.15	<0.068	10.33	6.88	6.39	2.40	<0.142