Donor | Log P* | Excised porcine cornea† | Human cornea construct | Porcine cornea construct† |
---|---|---|---|---|
*Partition coefficients P between 1-octanol and the aqueous formulations. | ||||
†Reichl and Müller-Goymann, 2001a,b; 2003. | ||||
Borocarpin S 2% | −1.3 | 8.57•10−6 (0.53•10−6) | 13.4•10−6 (3.01•10−6) | 35.6•10−6 (1.53•10−6) |
Glauconex 0.5% | −0.4 | 5.95•10−6 (0.52•10−6) | 9.88•10−6 (1.79•10−6) | 24.8•10−6 (4.79•10−6) |
HC 0.02% OK | 1.6 | 3.07•10−6 (0.99•10−6) | 5.41•10−6 (0.40•10−6) | 7.11•10−6 (1.21•10−6) |