Plasma and intraocular levels of cellular fibronectin in DM
| Plasma (μg/ml) | p Value* | Intraocular fluid (μg/ml) | p Value | Aqueous (μg/ml) | p Value | Vitreous (μg/ml) | p Value | |
|---|---|---|---|---|---|---|---|---|
| Mean (SD) (n) | Mean (SD) (n) | Mean (SD) (n) | Mean (SD) (n) | |||||
| *p Values result from Mann-Whitney tests, compared to control samples. | ||||||||
| DM = diabetes mellitus; DRP = diabetic retinopathy; MO = macular oedema; leakage = vascular leakage on fluorescein angiography. | ||||||||
| Controls | ||||||||
| DM | ||||||||
| Total | 3.00 (1.42) (10) | 0.27 | 2.58 (3.89) (11) | 0.007 | 0.38 (0.38) (4) | 0.19 | 3.84 (4.48) (7) | 0.045 |
| DRP+ | 3.24 (1.51) (7) | 0.16 | 3.46 (4.29) (8) | 0.002 | 0.58 (0.52) (2) | − | 4.42 (4.61) (6) | 0.016 |
| DRP− | 2.44 (1.27) (3) | 1.00 | 0.25 (0.12) (3) | 0.63 | 0.18 (0.02) (2) | − | 0.39 (1) | − |
| MO+ | 3.08 (1.59) (6) | 0.32 | 4.42 (4.62) (6) | 0.001 | −(0) | − | 4.42 (4.62) (6) | 0.016 |
| MO− | 2.88 (1.35) (4) | 0.46 | 0.24 (0.10) (4) | 0.65 | 0.19 (0.02) (3) | 0.48 | 0.39 (1) | − |
| Leakage+ | 3.24 (1.51) (7) | 0.16 | 3.82 (4.50) (7) | 0.002 | 0.211 (1) | − | 4.42 (4.61) (6) | 0.016 |
| Leakage− | 2.44 (1.27) (3) | 1.00 | 0.25 (0.12) (3) | 0.63 | 0.18 (0.02) (2) | − | 0.39 (1) | − |