Analysis of sex related differences of least squares (LS) mean HRT optic disc measurements in normal eyes, standard deviation (SD) of LS means, differences of LS means (male):LS means (female) with non-adjusted 95% confidence interval (CI) and with significance (covariance analysis for age and sex influence on HRT measurements, Bonferoni adjusted significance level p<0.004)
| Male (n = 728), mean age 45.4 (SD 7.7) years | Female (n = 154), mean age 53.6 (SD 9.3) years | Difference (95% CI) | p Value | |
|---|---|---|---|---|
| Mean LS (SD) | Mean LS (SD) | |||
| *Mean retinal nerve fibre layer thickness (HRT). | ||||
| †Significant. | ||||
| Disc area (mm2) | ||||
| RE | 1.82 (0.40) | 1.84 (0.44) | −0.024 (−0.098 to 0.049) | 0.51 |
| LE | 1.81 (0.40) | 1.79 (0.42) | +0.023 (−0.051 to 0.098) | 0.54 |
| Cup area (mm2) | ||||
| RE | 0.44 (0.32) | 0.44 (0.34) | −0.006 (−0.065 to 0.054) | 0.85 |
| LE | 0.44 (0.33) | 0.43 (0.34) | +0.012 (−0.048 to 0.072) | 0.69 |
| Cup:disc area ratio | ||||
| RE | 0.22 (0.14) | 0.22 (0.14) | −0.001 (−0.026;0.024) | 0.95 |
| LE | 0.22 (0.13) | 0.22 (0.14) | +0.004 (−0.021 to 0.029) | 0.75 |
| Rim area (mm2) | ||||
| RE | 1.38 (0.28) | 1.40 (0.29) | −0.019 (−0.070;0.032) | 0.47 |
| LE | 1.37 (0.29) | 1.36 (0.28) | +0.011 (−0.038 to 0.061) | 0.65 |
| Mean RNFLT (mm)* | ||||
| RE | 0.261 (0.067) | 0.277 (0.070) | −0.016 (−0.028 to −0.004) | 0.011 |
| LE | 0.251 (0.066) | 0.257 (0.069) | −0.006 (−0.018 to 0.006) | 0.34 |
| Rim volume (mm3) | ||||
| RE | 0.37 (0.14) | 0.40 (0.14) | −0.032 (−0.058 to −0.008) | 0.001† |
| LE | 0.36 (0.13) | 0.37 (0.13) | −0.012 (−0.035 to 0.012) | 0.33 |