Effect of doxycycline on the rates of alamar blue reduction by cultured epithelial cells and keratocytes (n = 6)
| Culture conditions | Rate of alamar blue reduction (RFU/min) | ||
|---|---|---|---|
| Epithelial cells | Keratocytes | ||
| Day 1 | Day 4 | Day 4 | |
| RFU, relative fluorescence units; LPS, lipopolysaccharide. | |||
| Control | 0.9 (0.3) | 1.1 (0.1) | 4.8 (0.4) |
| + LPS (10 μg ml−1) | 0.9 (0.2) | 0.9 (0.2) | 5.1 (0.4) |
| + Doxycycline (120 μm) | 0.9 (0.3) | 1.5 (0.4) | 1.6 (0.1) |
| + Doxycycline + LPS | 0.8 (0.2) | 1.6 (0.4) | 1.3 (0.1) |