Odds ratios (95% CI) on multivariate analysis for different cataract subtypes (nuclear, cortical, and PSC); subjects aged 40 years and older
| N = 2449 (%) | Nuclear (n = 2236) | Cortical (n = 717) | PSC (n = 1124) | Any cataract† (n = 2642) | Cataract operated (n = 482) | |
|---|---|---|---|---|---|---|
| *p<0.05. | ||||||
| †Includes any cataract and previously cataract operated in any eye cohort. | ||||||
| †Smoker categories based on quartiles of person cigarette years smoked. | ||||||
| ‡High waist to hip ratio = waist to hip ratio>0.8 for females, and >1.0 for males. | ||||||
| Age (years) | ||||||
| 40–49 | 325 (13.3) | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| 50–59 | 817 (33.4) | 6.90 (5.80 to 8.20)* | 4.22 (3.15 to 5.66)* | 4.16 (3.25 to 5.34)* | 6.7 (5.7 to 8.0)* | 4.00 (2.62 to 6.11) |
| 60–69 | 976 (39.8) | 22.22 (18.18 to 27.16)* | 9.06 (6.79 to 12.09)* | 11.22 (8.78 to 14.34)* | 39.4 (31.1 to 49.8)* | 13.38 (8.96 to 19.98) |
| 70 | 331 (13.5) | 18.34 (13.92 to 24.18)* | 12.26 (8.72 to 17.24)* | 15.14 (11.23 to 20.42)* | 96.2 (59.8 to 154.5)* | 25.39 (16.41 to 39.30) |
| Sex | ||||||
| Female | 1314 (53.6) | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| Male | 1135 (46.4) | 0.79 (0.65 to 0.96)* | 0.76 (0.59 to 0.97)* | 0.86 (0.69 to 1.07) | 0.78 (0.63 to 0.97)* | 1.04 (0.78 to 1.39) |
| No hypertension | 2035 (83.1) | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| Hypertension | 414 (16.9) | 1.07 (0.88 to 1.29) | 1.39 (1.11 to 1.72)* | 1.20 (0.98 to 1.46) | 1.00 (0.84 to 1.29) | 0.97 (0.74 to 1.27) |
| No diabetes | 2307 (94.2) | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| Diabetes | 142 (5.8) | 1.68 (1.21 to 2.34)* | 1.12 (0.77 to 1.65) | 1.55 (1.12 to 2.15)* | 2.46 (1.70 to 3.57)* | 1.60 (1.07 to 2.40) |
| Normal body mass index | 719 (29.3) | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| Lean | 1577 (64.4) | 1.37 (1.17 to 1.59)* | 1.18 (0.97 to 1.43) | 1.32 (1.11 to 1.57)* | 1.32 (1.12 to 155)* | 0.87 (0.70 to 1.10) |
| Overweight | 133 (5.4) | 0.75 (0.56 to 1.01)* | 1.38 (0.96 to 1.43) | 1.09 (0.77 to 1.53) | 0.83 (0.62 to 1.13) | 1.11 (0.71 to 1.74) |
| Obese | 20 (0.8) | 0.71 (0.36 to 1.38) | 0.41 (0.12 to 1.35) | 1.01 (0.46 to 2.19) | 0.87 (0.45 to 1.70) | 1.16 (0.46 to 3.17) |
| No PXF | 2205 (90.0) | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| PXF | 244 (10.0) | 1.26 (0.94 to 1.68) | 1.53 (1.17 to 2.01)* | 1.25 (0.97 to 1.61) | 3.37 (2.14 to 5.62)* | 2.43 (1.83 to 3.22) |
| Non-smoker† | 1790 (73.5) | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| Mild smoker | 120 (4.9) | 1.15 (0.82 to 1.61) | 0.97 (0.62 to 1.52) | 0.87 (0.59 to 1.27) | 1.20 (0.83 to 1.73) | 1.08 (0.67 to 1.73) |
| Moderate | 305 (12.5) | 1.28 (1.01 1.64)* | 1.36 (1.01 to 2.04)* | 1.01 (0.77 to 1.32) | 1.20 (1.05 to 1.57)* | 0.65 (0.44 to 1.0) |
| Heavy | 219 (9.0) | 1.06 (0.81 to 1.38) | 1.46 (1.05 to 2.03)* | 1.00 (0.74 to 1.39) | 1.1 (0.83 to 1.49) | 0.74 (0.49 to 1.12) |
| Illiterate | 1255 (51.5) | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| Literate | 1183 (48.5) | 0.50 (0.43 to 0.59)* | 0.70 (0.58 to 0.85)* | 0.74 (0.63 to 0.89)* | 0.41 (0.36 to 0.49)* | 0.70 (0.55 to 0.88) |
| Waist-hip ratio‡ | ||||||
| Normal | 453 (18.6) | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| High | 1983 (81.4) | 0.67 (0.54 to 0.82)* | 0.93 (0.73 to 1.18) | 0.77 (0.62 to 0.94)* | 0.58 (0.47 to 0.71)* | 0.88 (0.65 to 1.16) |