Differential gene expression between cultured RPE cells grown in serum and serum withdrawn conditions sorted by SAM with an FDR of 4.6% and at least a twofold differential expression threshold
| Gene name | GenBank Acc No | Score (d) | Fold change* | Biological function |
|---|---|---|---|---|
| *Serum withdrawn/serum conditions. | ||||
| 13 Genes overexpressed by cells grown in serum withdrawn medium | ||||
| Myeloid cell leukaemia sequence 1 (BCL2 related) | AA488674 | 2.87841767 | 11.5 | Apoptosis |
| Phytoceramidase, alkaline | W58013 | 2.60586649 | 2.8 | Apoptosis/ceramide metabolism |
| Reticulocalbin 1, EF-hand calcium binding domain | AA457719 | 2.67862204 | 3.2 | Calcium binding/signal transduction |
| Visinin-like 1 | H65066 | 2.60870158 | 8.6 | Calcium binding/signal transduction |
| Phytanoyl-CoA hydroxylase interacting protein | AA405628 | 3.75618502 | 8.3 | Development/differentiation |
| Leucine rich repeat containing 28 | R95132 | 2.99928312 | 6.9 | Development/differentiation |
| Ephrin-B1 | AA428778 | 2.7292518 | 3.2 | Development/differentiation |
| ATP binding cassette, subfamily C (CFTR/MRP), member 13 | H47929 | 3.63023830 | 6.7 | Ion transport |
| Ubiquitin conjugating enzyme E2D 3 (UBC4/5 homologue, yeast) | AA017199 | 2.72914196 | 3.8 | Protein degradation |
| RNA binding motif protein 4 | AA456271 | 2.79296662 | 2.9 | RNA processing |
| Chromosome 22 open reading frame 8 | H94903 | 3.71707843 | 6.3 | Unknown |
| IMAGE:3895112 | T95342 | 2.66350001 | 4.7 | Unknown |
| Mesoderm development candidate 2 | AA284495 | 2.79383791 | 2.3 | Unknown |
| 2 Genes underexpressed by cells grown in serum withdrawn medium | ||||
| v-myb myeloblastosis viral oncogene homolog (avian)-like 2 | AA456878 | −3.6013598 | −4.5 | Apoptosis/transcription factor |
| IMAGE:295501 | W23543 | −3.4456702 | −2.4 | Unknown |