Table 1

 Characterisation of retinal vasculature in the transgenic mouse lines

Retinal vasculature characteristicsLine 029Line 050/056Line 094
*Other pathological features observed through clinical and histological examinations.
Capillary non-perfusion+++
Microaneurysms+++
Venous dilatation++
Tortuosity of blood vessels++
Haemorrhages±++++
Neovascularisation+++++
Preretinal haemorrhage+++
Vitreous haemorrhage+++
Fibrovascular proliferation++
Cataracts*++++
Retinal detachment+++++