Characteristics of patients with TAO
| CAS, clinical activity score; EOM, extraocular muscles; TAO, thyroid associated orbitopathy; TRAB, thyrotropin receptor autoantibodies; TSHR, thyrotropin receptor. | |
| Number of patients: n = 30 | |
| Mean (range) age: 55.9 years (28–85) | |
| Sex: female: n = 22, male n = 8 | |
| Smokers: n = 19 | |
| Mean (range) TAO duration: 25.7 months (6–96) | |
| TAO severity: moderate n = 16, severe n = 14 | |
| CAS (0–7): | |
| 0 | n = 23 |
| 1 | n = 2 |
| 2 | n = 1 |
| 3 | n = 1 |
| 4 | n = 0 |
| 5 | n = 2 |
| Unknown in 1 patient | |
| Mean (range) TRAB level at the beginning: | |
| Not detectable | n = 6 |
| Positive | n = 22:50.64 U/l (2.3–212) |
| Unknown in 2 patients | |
| Mean (range) TRAB level at the biopsy: | |
| Not detectable | n = 4 |
| Positive | n = 26:25.392 U/l (2.4–213) |
| Unknown in 2 patients | |
| Number of TSHR+ cells in EOM biopsy: | |
| <5/field | n = 16 |
| 5–10/field | n = 11 |
| >10/field | n = 3 |