Age, sex, and risk factors in cases and controls
| Cases (n = 446) CNV only (n = 269) GA only (n = 107) Mixed GA/CNV (n = 70) | Controls (n = 283) | |
|---|---|---|
| Mean age (years (SD)) | 80.3 (6.9) | 75.6 (7.6) |
| Sex | ||
| Male | 204 (45.7%) | 117 (41.3%) |
| Female | 242 (54.3%) | 166 (58.7%) |
| Iris colour | ||
| Light | 381 (87.4%) | 248 (88.3%) |
| Dark | 55 (12.6%) | 33 (11.7%) |
| Change in iris colour | ||
| Lighter | 87 (20.0%) | 39 (13.9%) |
| Darker | 31 (7.1%) | 19 (6.8%) |
| Same | 317 (72.9%) | 223 (79.4%) |
| Worked/lived in sunny climate for ⩾5 years | ||
| Yes | 75 (17.2%) | 36 (12.8%) |
| No | 360 (82.8%) | 245 (87.2%) |
| Treatment for skin tumour | ||
| Yes | 26 (6.0%) | 14 (5.0%) |
| No | 410 (94.0%) | 267 (95.0%) |
| Skin sun sensitivity (skin type) | ||
| Sunburn prone | 133 (30.5%) | 68 (24.2%) |
| Sunburn resistant | 303 (69.5%) | 213 (75.8%) |
| Hair colour | ||
| Light | 107 (24.5%) | 58 (20.6%) |
| Dark | 330 (75.5%) | 223 (79.4%) |
| Mean sun exposure index (see text for explanation) (SD) | 25.6 (28.9) | 26.7 (31.9) |
| Sun avoidance measures taken | ||
| Yes | 390 (89.25) | 253 (90.4%) |
| No | 47 (10.8%) | 27 (9.6%) |
| Pack years of cigarette smoking | ||
| 0 | 165 (37.0%) | 112 (39.6%) |
| 0.1–20 | 125 (28.0%) | 108 (38.2%) |
| 20.1–40 | 103 (23.1%) | 49 (17.3%) |
| >40 | 53 (11.9%) | 14 (4.9%) |