Optic nerve head imaging measures in control eyes, unaffected patient eyes, and affected patient eyes
| Control eyes* (n = 15) | Unaffected patienteyes (n = 25) | Affected patienteyes (n = 25) | ||
|---|---|---|---|---|
| Values are mean (SD). pc values are comparisons between controls and patients. pf values are comparisons between unaffected fellow eyes and affected eyes in patients. | ||||
| *One randomly selected eye from each control subject was used. †This is a measure for the overall three dimensional shape of the optic disc cup and has no units. RNFL, retinal nerve fibre layer. | ||||
| Optic disc area (mm2) | 1.90 (0.48) | 2.02 (0.43) | 2.04 (0.36) | |
| pc = 0.42 | pc = 0.32 | |||
| pf = 0.84 | ||||
| Optic cup area (mm2) | 0.51 (0.49) | 0.51 (0.34) | 0.62 (0.44) | |
| pc = 0.97 | pc = 0.48 | |||
| pf = 0.17 | ||||
| Cup shape measure† | −0.23 (0.07) | −0.28 (0.42) | −0.17 (0.08) | |
| pc = 0.72 | pc = 0.01 | |||
| pf = 0.26 | ||||
| Neuroretinal rim area (mm2) | 1.39 (0.31) | 1.51 (0.36) | 1.42 (0.41) | |
| pc = 0.32 | pc = 0.83 | |||
| pf = 0.21 | ||||
| Neuroretinal rim volume (mm2) | 0.38 (0.22) | 0.40 (0.16) | 0.34 (0.19) | |
| pc = 0.80 | pc = 0.50 | |||
| pf = 0.04 | ||||
| Mean RNFL thickness at the disc edge (mm) | 0.24 (0.11) | 0.23 (0.08) | 0.19 (0.08) | |
| pc = 0.82 | pc = 0.08 | |||
| pf = 0.009 | ||||