Relapse rate before and during treatment with mycophenolate mofetil, change in level of inflammation and in visual acuity, side effects
| Patient | Diagnosis | Relapse rate before MMF treatment (/year) | Relapse rate after MMF treatment (/year) | Efficacy regarding relapse rate | Change in level of inflammation | Rate of visual acuity change (R/L) | Complications | Side effects before MMF treatment | Side effects during MMF treatment |
|---|---|---|---|---|---|---|---|---|---|
| ANA, antinuclear antibody; AU, anterior uveitis; IOP, intraocular pressure; IU, intermediate uveitis; JIA, juvenile idiopathic arthritis; L, left; MMF, mycophenolate mofetil; R, right; TINU syndrome, tubulointerstitial nephritis and uveitis syndrome. | |||||||||
| 1 | AU, ANA positive | 4 | 1 | Effective | Improved | 2/1 | No | Raised IOP | Headache |
| 2 | AU, ANA positive | 2.5 | 0.3 | Effective | Improved | 2/0 | No | No | No |
| 3 | IU, idiopathic | 1 | 0.3 | Effective | Improved | 0/3 | No | Raised IOP, growth retardation | No |
| 4 | IU, idiopathic | 1 | 1 | No response | No change | 1/3 | No | No | Headache |
| 5 | IU, idiopathic | 3 | 1.5 | Moderate | No change | 0/0 | No | Growth retardation, reduction of liver tests | No |
| 6 | AU, sarcoidosis | 1.5 | 1.0 | Moderate | Improved | 3/−3 | Secondary glaucoma | No | No |
| 7 | IU, idiopathic | 1.5 | 0.6 | Moderate | Improved | 6/0 | No | Secondary Cushing, acne | Headache |
| 8 | AU, TINU syndrome | 2 | No relapses | Effective | Improved | 4/2 | No | No | No |
| 9 | IU, idiopathic | 2 | 0.5 | Effective | Improved | 0/6 | No | No | No |
| 10 | Panuveitis, idiopathic | 2 | No relapses | Effective | Improved | 2/2 | No | Raised IOP, reduction of liver tests | Rash |
| 11 | IU, idiopathic | 2 | 0.5 | Effective | Improved | 0/−1 | Epiretinal membrane | Obesity, emotional liability | Headache, gastrointestinal discomfort |
| 12 | AU, ANA positive | 2 | 1 | Moderate | Improved | −6/−5 | Cataract | Raised IOP, secondary Cushing | No |
| 13 | IU, idiopathic | 2 | 0.3 | Effective | Improved | 0/6 | No | Raised IOP | No |
| 14 | IU, idiopathic | 2.5 | 0.5 | Effective | Improved | 0/4 | No | Emotional liability | No |
| 15 | IU, idiopathic | 1.5 | No relapses | Effective | Improved | 1/0 | No | No | Leucopenia |
| 16 | AU, JIA | 2 | 1 | Moderate | No change | 4/−1 | Secondary glaucoma | Secondary Cushing, anaphylactic reaction | No |
| 17 | IU, idiopathic | 2 | No relapses | Effective | Improved | 0/0 | No | Growth retardation | Rash |