Table 1 Clinical and genetic features of patients with cone–rod dystrophy

Case	Sex	Age	Genotype	Visual acuity	Fundus	AF	Colour vision
1	M	48	RPGR	6/60	Macular atrophy and pigmentation BE	Low-density AF over central macula surrounded by a ring of high density	Absent
			Pedigree A	6/60
			ORF15+A1094C G1095T	6/60
2	M	40	RPGR	6/9	Macular RPE atrophy BE	Low-density AF over central macula surrounded by a ring of high density	Absent
			Pedigree A	6/9
			ORF15+A1094C G1095T	6/9
3	M	37	RPGR	6/9	No definite abnormality	Low-density AF over the central macula surrounded by a ring of high density	Absent
			Pedigree A	6/18
			ORF15+A1094C G1095T	6/18
4	M	19	RPGRPedigree B	6/60	Mottling of RPE at macula	Small parafoveal ring of high density	Absent
4	M	19	ORF15+1176G>T	6/60	Mottling of RPE at macula	Small parafoveal ring of high density	Absent
5	M	52	RIMS1	6/60	Areas of macular atrophy and pigmentation BE. Attenuated vessels and peripheral areas of atrophy BE	Low-density AF centrally surrounded by a high-density ring	Mildly abnormal
5	M	52	Arg844His	6/60		Low-density AF centrally surrounded by a high-density ring	Mildly abnormal
6	F	82	RIMS1	6/60	Bilateral macular atrophy and attenuated vessels	BE: Low-density AF over central atrophy surrounded by a ring of higher density AF	Abnormal
6	F	82	Arg844His	6/60	Bilateral macular atrophy and attenuated vessels		Abnormal
7	F	53	RIMS1	3/60	Extensive RPE atrophy and patchy pigmentation RE>LE. Attenuated vessels	Low-density AF over central atrophy surrounded by a ring of high density	Abnormal
7	F	53	Arg844His	3/60			Abnormal
8	M	48	RIMS1Arg844His	6/9	RE: RPE changes.	RE: Central preservation surrounded by concentric rings of high density and patchy low-density AF	Mildly abnormal
8	M	48		6/9	LE: Well demarcated macular atrophy	LE: Low density lesion over atrophic area surrounded by ring of high density	Mildly abnormal
9	M	30	RIMS1	6/18	Extensive macular RPE atrophy and abnormal pigmentation LE>RE. Occasional scattered peripheral bone-spicule pigmentation	Low-density AF over central atrophy surrounded by a ring of high density. Narrow bridge of RPE sparing over central macula of RE	Mildly abnormal
9	M	30	Arg844His	3/60			Mildly abnormal
10	F	18	RIMS1	6/9	Mild bilateral RPE changes at maculae	Parafoveral ring of high-density AF, BE	Normal
10	F	18	Arg844His	6/5	Mild bilateral RPE changes at maculae	Parafoveral ring of high-density AF, BE	Normal

BE, both eyes; LE, left eye; RE right eye.