(A) Autoimmune-mediated group | | | |
Mononuclear cell infiltration zonal granulomatous inflammation around necrotic sclera | | 70-year-old male | Left eye with pain and marked inflammation |
| History of rheumatoid arthritis |
Mononuclear inflammation zonal granulomatous inflammation surrounding focal areas of collagen necrosis | | 77-year-old female | Right eye with right-sided facial pain and eye inflammation |
| (+) Rheumatoid factor |
| (+) ANA |
Necrosis and zonal granulomatous inflammation | | 73-year-old female | Right eye with pain |
| History of severe rheumatoid arthritis |
(B) Idiopathic group | | | |
Foci of scleral necrosis | | 51-year-old male | Right eye with chronic retinal detachment and necrotising scleritis |
No zonal pattern | |
Lymphocytes and plasma cells | |
Foci of scleral necrosis | | 55-year-old male | Right eye with scleral uveitis |
Plasma cells, lymphocytes, xanthoma-like cells, macrophages | |
Focal scleral necrosis | | 67-year-old male | Left eye with pain, weight loss and temporal ciliary body mass |
Polymorphonuclear leucocytes, lymphocytes, plasma cells | |