Table 1 Clinical information and demographics
Histopathological findingsDemographicsClinical information
(A) Autoimmune-mediated group
Mononuclear cell infiltration zonal granulomatous inflammation around necrotic sclera70-year-old maleLeft eye with pain and marked inflammation
History of rheumatoid arthritis
Mononuclear inflammation zonal granulomatous inflammation surrounding focal areas of collagen necrosis77-year-old femaleRight eye with right-sided facial pain and eye inflammation
(+) Rheumatoid factor
(+) ANA
Necrosis and zonal granulomatous inflammation73-year-old femaleRight eye with pain
History of severe rheumatoid arthritis
(B) Idiopathic group
Foci of scleral necrosis51-year-old maleRight eye with chronic retinal detachment and necrotising scleritis
No zonal pattern
Lymphocytes and plasma cells
Foci of scleral necrosis55-year-old maleRight eye with scleral uveitis
Plasma cells, lymphocytes, xanthoma-like cells, macrophages
Focal scleral necrosis67-year-old maleLeft eye with pain, weight loss and temporal ciliary body mass
Polymorphonuclear leucocytes, lymphocytes, plasma cells