Table 1 Effects of accumulated doses of indomethacin on ONPo2 under baseline conditions and after COX inhibition with NSAIDs other than indomethacin
Indomethacin dose (mg)BaselineAfter COX inhibition
ONPo2 change (kPa)ONPo2 change (kPa)
30.2 (0.1), 30.4 (0.1), 4
50.5 (0.1), 30.4 (0.2), 5
100.6 (0.2), 60.8 (0.5), 5
250.6 (0.2), 50.6 (0.2), 6
500.8 (0.3), 60.9 (0.6), 8
1000.8 (0.3), 51.7 (1.4), 2
1501.1 (0.4), 50.3), 1
  • Results are presented as the average (SD), followed by the number of experiments.