Table 2

Central foveal point thickness (CFPT) and macular volume measurements

CategoryCFPT (µm)Macular volume (mm3)
Ranibizumabp ValueBevacizumabp ValueRanibizumabp ValueBevacizumabp Value
Pretreatment278 (84)288 (94)7.22 (0.96)7.36 (1.08)
30 (14)227 (80)0.001†243 (95)0.058†6.69 (0.74)0.002†6.71 (1.18)0.028†
60 (14)251 (100)0.192†220 (55)0.008†7.14 (1.63)0.437†6.50 (0.42)<0.001†
90 (14)241 (85)0.128†246 (21)0.029†7.04 (1.16)0.337†7.04 (0.97)0.260†
Minimum CFPT227 (80)0.750‡220 (55)0.750‡6.69 (0.74)0.300‡6.50 (0.42)0.300‡

  • Standard deviations are shown in parentheses. CFPT and macular volume measurements before and at three post-treatment time points. The absolute minimums of central foveal point thickness and macular volume measurements were similar (p = 0.75 and p = 0.30, respectively), but the time required to achieve these minimums was different. All p values represent one-sided Student t tests assuming unequal variance compared with pretreatment measurements.

  • †p Values when compared with pretreatment levels.

  • ‡p Values when compared against the minimum value achieved by the other treatment.