Univariate analysis (log-rank test) | Multiple Cox regression analysis after forward and backward analysis | |||||
Variable | Category | No. of patients with recurrent tumour/total no. of patients | p Value | HR | 95% CI for HR | p Value |
Sex | Female | 10/73 | 0.19 | |||
Male | 16/68 | |||||
Age (years) | <50* | 8/62 | 0.09 | 2.6 | 1.0 to 6.6 | 0.046 |
≥50 | 18/79 | |||||
Baseline visual acuity (decimal) | <0.5 | 17/75 | 0.15 | |||
≥0.5 | 9/66 | |||||
Ciliary body infiltration | Yes | 18/103 | 0.78 | |||
No | 8/38 | |||||
Tumour thickness (mm) | ≤9.5 | 13/71 | 0.79 | |||
>9.5 | 13/69 | |||||
LBD (mm) | <16* | 12/92 | 0.00 | 2.4 | 1.1 to 5.6 | 0.035 |
≥16 | 14/43 | |||||
TDO (mm) | <10 | 11/72 | 0.24 | |||
≥10 | 15/61 | |||||
TDF (mm) | <10 | 9/58 | 0.46 | |||
≥10 | 10/43 | |||||
106Ru brachytherapy | Yes* | 19/124 | 0.04 | 4.5 | 1.8 to 11.1 | 0.001 |
No | 7/17 | |||||
Histological type | Spindle cell | 9/58 | 0.25 | |||
Mixed or epithelioid cell | 17/83 | |||||
Exudative retinal detachment | Yes | 24/97 | 0.01 | 7.8 | 1.0 to 59.3 | 0.046 |
No* | 1/34 |
↵* Reference category in Cox regression analysis.
LBD, largest tumour basal diameter; TDF, tumour distance to fovea; TDO, tumour distance to optic disc.